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Frank Schaeffel Selected Research

Myopia

10/2021A retrospective analysis of the therapeutic effects of 0.01% atropine on axial length growth in children in a real-life clinical setting.
2/2021Corneal Penetration of Low-Dose Atropine Eye Drops.
1/2021Emmetropic, But Not Myopic Human Eyes Distinguish Positive Defocus From Calculated Blur.
1/2021Effects of Single and Repeated Intravitreal Applications of Atropine on Choroidal Thickness in Alert Chickens.
11/2020Interactions of cone abundancies, opsin expression, and environmental lighting with emmetropization in chickens.
2/2020Studies on retinal mechanisms possibly related to myopia inhibition by atropine in the chicken.
1/2020Effects of 7-Methylxanthine on Deprivation Myopia and Retinal Dopamine Release in Chickens.
11/2019Demyelination and shrinkage of axons in the retinal nerve fiber layer in chickens developing deprivation myopia.
4/2019Changes in fundus reflectivity during myopia development in chickens.
1/2019Probing the Potency of Artificial Dynamic ON or OFF Stimuli to Inhibit Myopia Development.
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Frank Schaeffel Research Topics

Disease

50Myopia
10/2021 - 05/2002
11Hyperopia (Hypermetropia)
01/2021 - 11/2002
9Refractive Errors (Refractive Error)
11/2019 - 01/2004
7Ganglion Cysts (Ganglion)
03/2014 - 02/2004
1Body Weight (Weight, Body)
01/2020
1Demyelinating Diseases (Demyelinating Disease)
11/2019
1Astigmatism
12/2016
1Scotoma (Scintillating Scotoma)
01/2015
1Macular Degeneration (Age-Related Maculopathy)
10/2014
1Albinism
09/2014
1Degenerative Myopia
09/2014
1Osteosarcoma (Osteogenic Sarcoma)
12/2009
1Anisometropia
03/2009
1Mydriasis
03/2005

Drug/Important Bio-Agent (IBA)

24Retinaldehyde (Retinal)IBA
01/2021 - 05/2002
11AtropineFDA LinkGeneric
10/2021 - 03/2005
7Ophthalmic Solutions (Eye Drops)IBA
10/2021 - 03/2005
6Dopamine (Intropin)FDA LinkGeneric
01/2020 - 06/2010
5Messenger RNA (mRNA)IBA
11/2020 - 09/2004
5Glucagon (Glukagon)FDA Link
06/2010 - 11/2002
3Muscarinic AntagonistsIBA
01/2021 - 03/2005
3PlasticsIBA
01/2018 - 02/2007
2Peptides (Polypeptides)IBA
02/2020 - 06/2010
2Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
02/2020 - 06/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2014 - 12/2009
2Insulin (Novolin)FDA Link
01/2012 - 01/2009
22'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
03/2009 - 01/2004
1ConnexinsIBA
01/2021
1Small Cytoplasmic RNAIBA
01/2021
1Cone OpsinsIBA
11/2020
1N(alpha)- trinitrophenyl- His(1)- homo- Arg(12)- glucagonIBA
02/2020
1Clonidine (ST 155)FDA LinkGeneric
02/2020
1Nitric Oxide Synthase (NO Synthase)IBA
02/2020
1Brimonidine Tartrate (Alphagan)FDA LinkGeneric
02/2020
17-methylxanthineIBA
01/2020
1Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
11/2019
1TabletsIBA
07/2018
13,4-Dihydroxyphenylacetic AcidIBA
01/2016
1Macular PigmentIBA
01/2015
1Bevacizumab (Avastin)FDA Link
10/2014
1Humanized Monoclonal AntibodiesIBA
10/2014
1Sulpiride (neogama)IBA
09/2014
1QuinpiroleIBA
09/2014
1ApomorphineFDA Link
09/2014
1Dopamine Agonists (Dopamine Agonist)IBA
09/2014
1SCH 23390IBA
09/2014
1Dopamine Agents (Dopaminergic Agents)IBA
09/2014
12,3,4,5- Tetrahydro- 7,8- dihydroxy- 1- phenyl- 1H- 3- benzazepine (SKF 38393)IBA
09/2014
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2012
1Dopamine AntagonistsIBA
10/2010
1Transforming Growth Factor beta2IBA
06/2010
1EnzymesIBA
06/2010
1Transforming Growth Factor beta1 (TGF beta 1)IBA
06/2010
1Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2009
1Mydriatics (Cycloplegics)IBA
07/2007
1Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
02/2007
1Transcription Factors (Transcription Factor)IBA
01/2007
1Apolipoprotein A-I (Apolipoprotein A1)IBA
11/2006
1PPAR alphaIBA
11/2006
1GW 7647IBA
11/2006
1Fibrillar CollagensIBA
04/2006
1GlycosaminoglycansIBA
04/2006
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
04/2006
1PirenzepineIBA
03/2006
1Gallamine Triethiodide (Gallamine)FDA Link
03/2006
1himbacineIBA
03/2006
1Cholinergic Agents (Cholinergics)IBA
03/2006
1Oxyphenonium (Oxyphenonium Bromide)FDA Link
03/2006
1SolutionsIBA
03/2006
14- diphenylacetoxy- 1,1- dimethylpiperidiniumIBA
03/2006
1Proteins (Proteins, Gene)FDA Link
04/2005
1Pharmaceutical PreparationsIBA
03/2005
1Proglucagon (Glucagon Precursors)IBA
09/2004
1Glucagon Receptors (Glucagon Receptor)IBA
09/2004

Therapy/Procedure

14Lenses
01/2021 - 02/2004
4Injections
09/2014 - 02/2004
3Intravitreal Injections
01/2020 - 02/2007
3Telescopes
03/2009 - 03/2006
2Therapeutics
09/2017 - 01/2003
2Eyeglasses (Spectacles)
08/2009 - 07/2007
1Enteral Nutrition (Feeding, Tube)
01/2020
1Meridians (Jing Luo)
12/2016
1Eye Protective Devices (Goggles)
11/2015
1Intraperitoneal Injections
02/2007
1Aftercare (After-Treatment)
02/2004
1Post and Core Technique (Technique, Post)
01/2004